#CHARGAFFRULE|#MOLECULAR TECHNIQUES|#MOLECULAR BIOLOGY BASICS|#molecular pathology|#DNA|#EKDINKAraja

#TP53|#ASTROCYTOMA|#MOLECULARPROFILEOFASTROCYTOMA|#EKDINKARAJAPATHOLOGYNOTES|#MOLECULARPATHOLOGY

#molecular|#MPN|#ekdinkarajapathologynotes|#who 2022 update|#JMML|#change in the diagnostic criteria

#who|#MDS|#WHO2022|#ekdinkarajapathologynotes|#BIALLELIC TP53 INACTIVATION|#SF3B1|#childhood MDS|

#ICC2022|#MYELOID NEOPLASMS WITH MUTATED TP53|#ekdinkarajapathologynotes|#molecular|#who2022|#TP53

#DNA POLYMERASE ENZYME|#molecular|#ekdinkarajapathologynotes|#PCR|thermostable taq polymerase|

#pcr|#polymerasechainreaction |#DNAPOLYMERASE|#molecular|#ekdinkarajapathologynotes|#POLYMERASE|

#ekdinkarajapathologynotes|#molecular|#DPYD|#DPYD genotyping|#dihydropyrimidine dehydrogenase|#5FU|

#molecular|#ekdinkarajapathologynotes|#SYBR GREEN|#nonspecific DNA binding dye|#rtpcr|#pcr|#realtime

#ekdinkarajapathologynotes|#molecular|#MYCN|#NMYC|#NERROBLASTOMA|#amplification of MYCN|#aggressive|

#realtime|#molecular|#ekdinkarajapathologynotes|#realtimePCR|#polymerasechainreaction|#reporter DYE|

#ultrapurewater|#types of water used in lab|#molecular|#ekdinkarajapathologynotes|#type1water|#type4

#ekdinkarajapathologynotes|#molecular|#sangersequencing|#dNTP|#ddNTP|#DIDEOXYNUCLEOTIDE|#DEOXYNUCLEO

#pharmacogenomics|#DPD|#DPYD|#5fluorouracil|#ekdinkarajapathologynotes #molecular|

#Basics of cell biology by Dr.Sai -part 1#ekdinkarajapathologynotes #molecular#cell#Cell organelles

#liquid biopsy|#cell free DNA|#cfDna|#molecular|#molecular_biology|#molecularsolid|#molecularpath|

#Harmonizing cell free DNA Guidelines|#molecular|#ekdinkarajapathologynotes| #molecular_biology|

#umi #unique molecular identifier#barcoding in NGS#Error corrected sequencing #molecular barcodes

#molecular #ekdinkarajapathologynotes #cell free DNA#CELLFREE UMOUR DNA#liquid biopsy#molecularsolid

#pcr#molecularbiology #moleculardiagnostics #pcr controls #negative control#positivecontrol#NTC#PC

STRUCTURE OF MOLECULAR REPORT

#ekdinkarajapathologynotes #inherited cancer #germline mutation #synchronous tumour#metachronous

#ekdinkarajapathologynotes#molecularpath #moleculardiagnostics #NGS #sequencing #PCR #amplification

#HLA typing #ekdinkarajapathologynotes #molecular

#DNA Methylation analysis #methylation #unmethylation #ekdinkaraja #moleculardiagnostics

#molecular assay|#AR Molecular pathology|#molecularsolid #moleculardiagnostics| #moleculargenetics|

#medical genetics #ekdinkarajapathologynotes # case discussion #DM preparation #AR MOLECULAR patholo

#genetic variation #ekdinkarajapathologynotes #genetics

#OPTICAL GENOME MAPPING # NON-SEQUENCING TECHNOLOGY #ekdinkarajapathologynotesGENOMES #OGM

#ASH24 of a trial of Atezolizumab combined with Venetoclax and Obinutuzumab as a first-line rx #CLL

# lenvatinib #pembrolizumab #pMMR #EndometrialCancer #Immunotherapy #Oncology #ASCO #OncoAlert

In young BRCA carriers Risk-reducing mastectomy (RRM) and salpingo-oophorectomy (RRSO)

#Trastuzumab emtansine (TDM1), #TDXd, #ADCs#Sacituzumab govitecan #datopotamab deruxtecan (Dato DXd)

#Bruton tyrosine kinase inhibitors # B-cell lymphoma-2 (BCL2) inhibitors# anti-CD20 #CLL/SLL

#NSCLC#EGFR exon 19 deletion#L858R #G718X #ekdinkarajapathologynotes#news S768I

#Bokhman's dualistic classification #type 1 endometrial cancer #type 2 endometrial cancer #estrogen

#Polymerase epsilon (POLE) #Somatic mutations #proofreading #exonuclease domain#ultramutated

#MMR #endometrial cancer#Microsatellite instability#news#ekdinkaMMR genes #MLH1# MSH2# MSH6# PMS2

# p53 immunostaining#TP53 sequencing #POLE wild type #MMR proficient #endometrial carcinomas.

#ekdinkarajapathologynotes#NSMP EC #POLE #MMR deficiency #TP53 mutation# intermediate prognosis

#cancerprogression #tumorprogression #adenocarcinoma #hallmarkofcancer #chemoresistance #carcinoma

#Tumors with chromosomal instability (CIN)#Frequent mutations of the tumor suppressor TP53

#gastric cancer#ekdinkarajapathologynotes #moleculardiagnostics#molecular biology #precisiontherapy

# lung adenocarcinoma#squamous cell carcinoma #large-cell lung carcinoma

#KRA #CRC #RAS pathway #poor prognosis#predictive of responses to EGFR therapy #most common mutation

Concurrent inhibition of ER together w dual anti-HER2 therapy #HER2-positive# breast cancer #tnbc

# metastatic colorectal cancer#KRAS #EGFR inhibitors#Drugs directly targeting KRAS #mutant KRASG12

#bladder cancer #molecular diagnostics #molecular biology #precision medicine #precision oncology

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#ekdinkarajapathologynotes #biology #molecular_biology #molecular diagnostics #BMT#COMPLICATION#VOD

#ekdinkarajapathologynotesSelinexor#myelofibrosis #ruxolitinib #SENTRY trial#molecular#science #news

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